Poly(vinyl alcohol)/Gelatin Scaffolds Allow Regeneration of Nasal Tissues

Need for regeneration and repair of nasal tissues occurs as a consequence several pathologies affecting the nose, including, but not limited to infective diseases, traumas tumor resections. A platform tissue was set up using poly(vinyl alcohol)/gelatin sponges with 20%–30% (w/w) gelatin content be used scaffolds, their intrinsic hydrophilic, cell adhesive shape recovery properties. We propose mesodermal progenitor cells (MPCs) isolated from bone marrow unique stem source obtaining different connective including vascular tissue. Finally, epithelial immune response these scaffolds assessed in vitro an environment containing inflammatory molecules. The results showed that mesenchymal stromal (MSCs) deriving MPCs could differentiate into cartilage fibrous tissue; whereas, combination endothelial still MPCs, pre-vascularized bone. scaffold did significantly alter insults derived interaction bacterial